Director, Commercial Transformation

Company: Sanofi
Location: Cambridge
Posted on: March 20, 2026

Job Description:

Job Title: Director, Commercial Transformation Location: Cambridge, MA About the Job Join the team transforming care for people with immune challenges, rare diseases, cancers, and neurological conditions. In Specialty Care, youll help deliver breakthrough treatments that bring hope to patients with some of the highest unmet needs. At Sanofi, we chase the miracles of science to improve people's lives. As a global leader in healthcare innovation, we're transforming the practice of medicine through breakthrough science and cutting-edge experimentation that drives meaningful change for patients worldwide. We're seeking a dynamic Director of Commercial Transformation who will focus initially on Experimentation Orchestration & Program Management on our Sanofi SPC Commercial Engagement Model (CEM) Program. The CEM program is a top leadership priority that will define Sanofi SPCs future commercial model in light of changing external landscape and our upcoming launches. The successful candidate will serve as the strategic connective tissue across ongoing experimentation initiatives and enable data-driven decision-making that will codify learnings and accelerate innovation at scale. You will synthesize complex insights, maintain program integrity, and help translate experiment outcomes into actionable business results that ultimately improve patient outcomes. This is a critical leadership position where you'll partner with senior executives, cross-functional teams, and key stakeholders to build our future operating model. If you're passionate about driving organizational transformation through disciplined program management and change leadership, this role offers an exceptional opportunity to make a lasting impact on how we innovate and deliver for patients. About Sanofi: Were an R&D-driven, AI-powered biopharma company committed to improving peoples lives and delivering compelling growth. Our deep understanding of the immune system and innovative pipeline enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve peoples lives Main Responsibilities: Command Center & Decision Enablement Serve as the central "source of truth" for experiment status, outcomes, and strategic insights across all initiatives Function as "connective tissue" that collates and synthesizes inputs across CEM stakeholders including experiment leads, analytics teams, change management, and strategic partners Active CEM stakeholder management to ensure engagement of the right stakeholders, at the right time Develop executive-ready materials and presentations to support critical scale/no-scale decisions Proactively identify and facilitate resolution of issues, tradeoffs, and escalations to senior leadership Program Orchestration Establish clear pathways for core teams by defining milestones, sprint cadences, and performance expectations while breaking down larger strategic objectives into achievable near-term goals Own and maintain the integrated roadmap, sequencing, and dependency management across all experimentation initiatives Drive rigorous tracking of progress, risks, and critical decision points across the entire experiment portfolio Ensure disciplined execution of stage-gates, pre-mortems, and executive review processes Facilitate the process of testing, learning and calibrating the teams approach to delivering work Change Management & Communications Orchestration Collaborate on and provide strategic input into existing CEM change management strategies and frameworks Partner with cross-functional teams (GTMC, L&D, P&C, etc.) to assess, develop, and disseminate content required for successful change management execution Act as primary conduit to communicate program impacts, implications, and strategic direction to all stakeholders Champion NA SPC AI upskilling goals and drive related capability-building initiatives Enabling Teams Ways of Working Establish and reinforce consistent experiment standards, metrics, and governance frameworks across the organization Collaborate with change management teams to embed new ways of working that drive sustainable transformation Build organizational capabilities to ensure experimentation becomes repeatable, scalable, and self-sustaining Lead the strategic transition of ownership from external partners to internal teams Monitor overall team health and actively identify, assess and address issues when they arise About You Education & Experience: You have a bachelors degree required; an MBA, Organizational Development, or related field strongly preferred You bring 10-12 years of progressive experience in program/portfolio management, strategy, transformation, or management consulting You have experience leading enterprise-wide transformation or change initiatives You ideally have a background in top-tier consulting (Big 4, MBB, or boutique strategy firms), internal strategy offices, transformation/PMO functions, or enterprise change management What You'll Bring: Exceptional program and portfolio management capabilities with the ability to manage multiple complex initiatives simultaneously while maintaining strategic focus Comfort operating in ambiguity with incomplete informationyou thrive in dynamic environments and can navigate uncertainty with confidence Outstanding executive communication skills with the ability to synthesize complex information into clear, actionable insights that drive decision-making Strategic mindset balanced with operational rigor and execution excellenceyou can think big picture while ensuring flawless delivery Experience with test-and-learn methodologies, analytics-driven decision-making, and agile ways of working Proven ability to influence without authority across highly matrixed organizations, building consensus and driving alignment Track record of enabling accountability and driving alignment across diverse stakeholder groups including brand teams, analytics teams, technology partners, and change management functions Background leading or deeply collaborating on change and communications efforts in large, complex organizations Strong problem-solving abilities with a data-driven approach to decision-making and risk management Passion for building organizational capabilities and developing talent Preferred Qualifications: Experience in pharmaceutical, healthcare, or life sciences industry Familiarity with AI/ML experimentation or digital transformation initiatives Experience with analytics tools and data visualization platforms Background in agile/scrum methodologies Why Choose Us? Bring the miracles of science to life alongside a supportive, future-focused team. Discover endless opportunities to grow your talent and drive your career, whether its through a promotion or lateral move, at home or internationally. Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact. Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks gender-neutral parental leave. Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law. GD-SG LI-GZ LI-Onsite vhd All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.

Keywords: Sanofi, Weymouth , Director, Commercial Transformation, IT / Software / Systems , Cambridge, Massachusetts